Peripheral Neuropathy & Nerve Health in Honolulu, Kailua-Kona & Hilo, Hawaii
The tingling, burning, numbness, and stabbing pain of peripheral neuropathy can be relentless — disrupting your sleep, limiting your balance, and making every step feel uncertain. Standard medications like gabapentin and pregabalin can blunt the symptoms, but they do nothing to address the underlying nerve damage. At Hawaii Wellness Clinic in , our regenerative medicine specialists offer advanced therapies that target the biological roots of peripheral neuropathy — improving nerve circulation, stimulating nerve repair, and restoring healthy sensation and function without long-term reliance on medications.
What Is Peripheral Neuropathy?
Peripheral neuropathy refers to damage or dysfunction of the peripheral nerves — the extensive network of nerves outside the brain and spinal cord that carry sensory, motor, and autonomic signals between the central nervous system and the rest of the body. When peripheral nerves are injured, compressed, or deprived of adequate blood supply and nutrients, they begin to misfire or fail to transmit signals properly — producing the characteristic symptoms of burning, tingling, numbness, shooting pain, and weakness that define neuropathic conditions.
Peripheral neuropathy can affect sensory nerves (producing pain and altered sensation), motor nerves (causing weakness and coordination problems), or autonomic nerves (disrupting functions like blood pressure regulation, digestion, and bladder control). The condition may involve a single nerve (mononeuropathy), multiple specific nerves (multiple mononeuropathy), or widespread nerve involvement (polyneuropathy). Common causes of peripheral neuropathy treated at Hawaii Wellness Clinic include diabetic neuropathy — the most prevalent cause, resulting from chronic high blood sugar damaging peripheral nerve fibers, chemotherapy-induced peripheral neuropathy (CIPN), alcohol-related neuropathy, autoimmune neuropathies including those associated with lupus and rheumatoid arthritis, vitamin B12 deficiency neuropathy, hypothyroid neuropathy, idiopathic neuropathy (where no specific cause can be identified), and post-herpetic neuralgia following shingles. Early and aggressive intervention is essential — peripheral neuropathy tends to progress when left untreated, and the window for meaningful nerve regeneration is best seized before irreversible structural damage occurs.
Signs That Suggest Peripheral Neuropathy
Common symptoms that may indicate peripheral neuropathy include tingling, burning, or electric shock-like sensations in the hands or feet, numbness or a feeling of wearing gloves or socks when you are not, sharp or shooting pain in the arms or legs, extreme sensitivity to light touch or temperature, muscle weakness or loss of coordination, balance problems and an increased risk of falls, swelling, discoloration, or unusual coldness in the extremities, and difficulty walking or performing fine motor tasks. If you have tried gabapentin, Lyrica, duloxetine, or other standard neuropathy medications without adequate relief, our regenerative approach may offer a meaningful path forward.
Our Regenerative Approach to Peripheral Neuropathy Treatment
At Hawaii Wellness Clinic in , we take a biologically targeted approach to peripheral neuropathy — using regenerative therapies that improve nerve blood supply, stimulate nerve fiber regeneration, reduce neuroinflammation, and address the underlying metabolic and nutritional deficiencies that often perpetuate nerve damage. All injection-based procedures are performed under ultrasound visualization for precision and safety.
PRP Therapy for Nerve Repair
PRP contains a rich concentration of growth factors — including nerve growth factor (NGF) and vascular endothelial growth factor (VEGF) — that support peripheral nerve regeneration and improve the microvascular environment around damaged nerve fibers. PRP delivered into the tissue surrounding affected nerves can improve local circulation, reduce neuroinflammation, and stimulate axonal regrowth. Learn more about PRP Therapy.
Biologic Cell Therapy for Neuropathy
For patients with more advanced peripheral neuropathy, Biologic Cell Therapy provides a deeper level of regenerative support — delivering concentrated growth factors and neurotrophic proteins that promote nerve and vascular regeneration, restore healthy nerve conduction, and support the repair of myelin sheaths damaged by chronic neuropathic conditions.
Class IV Laser Therapy
Class IV Laser Therapy is a powerful non-invasive tool for peripheral neuropathy — stimulating mitochondrial energy production in nerve cells, improving endoneurial microcirculation, and reducing neuroinflammation. Multiple clinical studies have documented meaningful improvements in neuropathic pain, sensation, and balance following a course of laser therapy. Learn more about our Class IV Laser Therapy.
Shockwave Therapy
Shockwave therapy improves tissue oxygenation and blood flow in chronically ischemic areas, reducing the vascular insufficiency that is a key driver of neuropathic damage in diabetic and other peripheral neuropathy patients. Learn more about our Shockwave Therapy program.
NAD⁺ Therapy for Nerve Health
NAD⁺ plays a critical role in axonal integrity and peripheral nerve health. NAD⁺ depletion — which occurs with aging, diabetes, chemotherapy, and chronic illness — accelerates peripheral nerve degeneration. Our intravenous NAD⁺ infusions restore cellular NAD⁺ levels, supporting mitochondrial function in nerve cells, reducing oxidative stress, and improving the neurological energy metabolism needed for nerve repair and regeneration. Learn more about NAD⁺ Therapy for Pain Recovery and NAD⁺ Wellness Therapy.
IV Vitamin Therapy for Nutritional Nerve Support
Nutritional deficiencies — particularly in B12, B1 (thiamine), B6, alpha-lipoic acid, and magnesium — are among the most common and most correctable contributors to peripheral neuropathy. Our high-dose IV nutrient infusions deliver these essential neuroprotective compounds directly into the bloodstream for immediate bioavailability, rapidly correcting deficiencies that oral supplementation cannot address as effectively. Explore our IV Vitamin Therapy options.
Why Choose Hawaii Wellness Clinic for Peripheral Neuropathy?
At Hawaii Wellness Clinic in , we take peripheral neuropathy seriously as a progressive condition that deserves more than medication management. Our board-certified specialists design comprehensive, biologically targeted treatment plans that address nerve damage at multiple levels — vascular, metabolic, nutritional, and regenerative — to produce the most meaningful and lasting improvements possible. Our aloha-inspired clinics across O’ahu, Hawai’i Island, and Maui provide a comfortable, supportive environment where your neurological health and quality of life are always our focus. Call us at (808) 201-2343 - Honolulu Office , (808) 201-2343 - Kailua Kona Office or (808) 201-2343 - Hilo Office to schedule your neuropathy consultation today.
Frequently Asked Questions About Peripheral Neuropathy Treatment in Hawaii
What causes peripheral neuropathy?
The most common cause is diabetes — chronic high blood sugar gradually damages the small blood vessels supplying peripheral nerves, leading to ischemic nerve injury. Other common causes include chemotherapy, alcohol abuse, autoimmune diseases, vitamin B12 deficiency, thyroid disorders, and infections such as shingles. In some cases, no specific cause can be identified (idiopathic neuropathy). Our team performs a thorough evaluation to identify treatable contributing factors in every patient.
Can peripheral neuropathy be reversed?
The degree of reversibility depends on the severity and duration of nerve damage, as well as the underlying cause. Early and mild neuropathy — particularly when driven by correctable factors such as nutritional deficiency, poor blood sugar control, or vascular insufficiency — has the best potential for improvement with regenerative intervention. Even in more advanced cases, meaningful reductions in pain, improved sensation, and better balance are achievable goals. Early intervention produces the best outcomes.
Is regenerative therapy safe for patients with diabetic neuropathy?
Yes. Our regenerative therapies — including PRP, laser therapy, NAD⁺ infusions, and IV nutrient therapy — are designed to be safe and effective for patients with diabetes. We take your full medical history, current medications, and glycemic control into account when designing your treatment plan to ensure maximum safety and effectiveness.
How does laser therapy help peripheral neuropathy?
Class IV Laser Therapy stimulates mitochondrial energy production within nerve cells, improves the microvascular blood supply to peripheral nerves, and reduces neuroinflammation — three of the core mechanisms driving peripheral neuropathy progression and symptoms. Multiple clinical studies have documented improvements in neuropathic pain, sensory testing scores, and balance in neuropathy patients following a course of laser treatment.
How many treatments are needed for peripheral neuropathy?
Most patients undergo an initial course of 8 to 12 laser or shockwave sessions combined with a series of NAD⁺ and IV nutrient infusions, followed by ongoing maintenance as appropriate. The exact plan depends on the underlying cause, severity of nerve damage, and individual response to therapy. Your provider will outline a personalized treatment timeline at your initial consultation.
Does Hawaii Wellness Clinic offer peripheral neuropathy treatment at multiple locations?
Yes. We provide peripheral neuropathy and nerve health treatment at our clinic locations in Honolulu (O’ahu), Kailua-Kona, and Hilo (Hawai’i Island). Call (808) 201-2343 - Honolulu Office , (808) 201-2343 - Kailua Kona Office or (808) 201-2343 - Hilo Office to find the most convenient location or to schedule your consultation.
Can peripheral neuropathy treatment be combined with other therapies at Hawaii Wellness Clinic?
Absolutely. Peripheral neuropathy frequently co-exists with chronic pain, ankle and foot conditions, and metabolic disorders that benefit from a comprehensive, integrated treatment approach. Our team coordinates all aspects of your care to ensure a cohesive, synergistic treatment plan.